Don't mess with the machine — evaluation of fluconazole susceptibility testing for Candida glabrata using the new VITEK2 AST-YS08 card following species modification

Maya Korem; Yuval Geffen; Sharon Amit

doi:10.1016/j.diagmicrobio.2019.114896

Don't mess with the machine — evaluation of fluconazole susceptibility testing for Candida glabrata using the new VITEK2 AST-YS08 card following species modification

Maya Korem, Yuval Geffen, Sharon Amit^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A modification of fluconazole formulation in the VITEK2 AST-YS08 card revoked the fluconazole–Candida glabrata combination. An evaluation of AST-YS08 following C. glabrata to C. albicans adjustment within VITEK2 software revealed higher fluconazole MICs compared to AST-YS07 and E-test, with major discrepancies. This mandates an alternative approach to fluconazole–C. glabrata susceptibility testing.

Original language	English
Article number	114896
Journal	Diagnostic Microbiology and Infectious Disease
Volume	96
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2019.114896
State	Published - Feb 2020
Externally published	Yes

Keywords

AST-YS08 card
Candida glabrata
Susceptibility testing
VITEK2

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10.1016/j.diagmicrobio.2019.114896

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title = "Don't mess with the machine — evaluation of fluconazole susceptibility testing for Candida glabrata using the new VITEK2 AST-YS08 card following species modification",

abstract = "A modification of fluconazole formulation in the VITEK2 AST-YS08 card revoked the fluconazole–Candida glabrata combination. An evaluation of AST-YS08 following C. glabrata to C. albicans adjustment within VITEK2 software revealed higher fluconazole MICs compared to AST-YS07 and E-test, with major discrepancies. This mandates an alternative approach to fluconazole–C. glabrata susceptibility testing.",

keywords = "AST-YS08 card, Candida glabrata, Susceptibility testing, VITEK2",

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Don't mess with the machine — evaluation of fluconazole susceptibility testing for Candida glabrata using the new VITEK2 AST-YS08 card following species modification

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Keywords

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