Donor Lungs Evaluation

Louis Stein, Alex Leung, Yaron D. Barac, Mani Daneshmand, Yuri Pesachovitz

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Lung transplantation remains as a vital treatment for patients with end-stage lung disease. The successful transplant of an allograft begins with the allocation of a suitable graft to an appropriate recipient. Donor lungs are considered a scarce resource which can provide the recipient years of an improved quality of life. Donation after brain death has traditionally been the source of lung grafts and remains the source of >90% of lung transplants. Living donor lobar lung transplantation is the newest source of donor lung allograft. The utility of lobar transplantation, as an alternative to whole lung transplant, was first described in infants. ABO compatibility plays a role in all solid-organ transplants. The preretrieval evaluation of the donor’s viral serologies is essential. The presence of human immunodeficiency virus, hepatitis B, hepatitis C, or cytomegavirus can influence treatment options.

Original languageEnglish
Title of host publicationTextbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease
Publisherwiley
Pages1110-1118
Number of pages9
ISBN (Electronic)9781119633884
ISBN (Print)9781119633846
DOIs
StatePublished - 1 Jan 2023

Keywords

  • ABO compatibility
  • donation after brain death
  • end-stage lung disease
  • hepatitis B
  • hepatitis C
  • human immunodeficiency virus
  • living donor lobar lung transplantation
  • lung transplantation

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