TY - JOUR
T1 - Does luminal gastrin stimulate gastric acid secretion?
AU - Ayalon, Amram
AU - Yazigi, Raul
AU - Devitt, Peter
AU - Rayford, Phillip L.
AU - Thompson, James C.
N1 - Funding Information:
From the Department of Surgery, The University of Texas Medical Branch, Galveston, Texas. Supported by a grant from the John A. Hartford Foundation, Inc., New York, New York, and Grant AM 15241 from the National Institutes of Health, Bethesda, Maryland.
PY - 1981/1
Y1 - 1981/1
N2 - The effects of pentagastrin on acid secretion, short circuit current, electrical conductance and potential difference were determined in isolated bullfrog fundic mucosa. Biologically active luminal pentagastrin had no effect on gastric mucosa, even at a concentration 100 times higher than that necessary for stimulation of the mucosa from the serosal side. It is concluded that luminal gastrin does not appear to have a physiologic role in gastric secretory processes.
AB - The effects of pentagastrin on acid secretion, short circuit current, electrical conductance and potential difference were determined in isolated bullfrog fundic mucosa. Biologically active luminal pentagastrin had no effect on gastric mucosa, even at a concentration 100 times higher than that necessary for stimulation of the mucosa from the serosal side. It is concluded that luminal gastrin does not appear to have a physiologic role in gastric secretory processes.
UR - http://www.scopus.com/inward/record.url?scp=0019364338&partnerID=8YFLogxK
U2 - 10.1016/0002-9610(81)90019-2
DO - 10.1016/0002-9610(81)90019-2
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0019364338
VL - 141
SP - 94
EP - 97
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 1
ER -