Do Intraocular Pressure Measurements under Anesthesia Reflect the Awake Condition?

Nina Gofman, Barak Cohen*, Idit Matot, Anat Cattan, Gad Dotan, Chaim Stolovitch, Noa Ela-Dalman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Anesthesia or sedation is needed when intraocular pressure (IOP) measurement is required in certain circumstances. The effect of different anesthetic regimens on the IOP is still debatable. We aimed to evaluate alterations in the IOP under anesthesia with either propofol or different end-tidal concentrations of sevoflurane, when compared with the awake state. Methods: The IOP was measured in both eyes of 20 adult patients undergoing extraocular ophthalmic surgeries at 5 timepoints: before the induction of general anesthesia (under topical anesthesia), after the induction using propofol target-controlled infusion, and under 3 end-tidal concentrations of sevoflurane (0.5%, 2%, and 5%), either in a decreasing (group A) or an increasing (group B) concentration order. Results: With either propofol or sevoflurane anesthesia, the IOP did not differ significantly from the measurement performed during the awake state (no anesthesia), regardless of the concentration of sevoflurane used (in the range of 0.5% to 5%) or the order of sevoflurane administration (from low to high concentration or vice versa). Conclusions: These data suggest that propofol and sevoflurane are valid anesthetic agents for the evaluation of IOP in adults when anesthesia is needed.

Original languageEnglish
Pages (from-to)299-302
Number of pages4
JournalJournal of Glaucoma
Issue number4
StatePublished - 2017


  • anesthetic agents
  • intraocular pressure
  • propofol
  • sevoflurane


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