@inproceedings{13c2b6f8838d4b8a9977c771389f5ccc,
title = "DNA sample cleanup using deterministic lateral displacement",
abstract = "Optical mapping relies on the preparation of fluorescent DNA. DNA must be imaged with good signal to noise and therefore the background of unwanted DNA fragments, fluorescent dyes and other reagents need to be removed. We use deterministic lateral displacement to separate 48.5 kbp DNA from < 10 kbp DNA. We also show the removal of 48.5 kbp DNA fragments from a background of fluorescent ATTO647N molecules and the recovery of >50 kbp molecules from a background of shorter digested fragments. In both cases improving signal to noise during imaging.",
keywords = "DNA, Deterministic lateral displacement, Sample cleanup, Separation",
author = "Rebekah Kim and Alexandra K{\"u}hnlein and Smith, {Darren A.} and Ho, {Bao Dang} and Assaf Grunwald and Beech, {Jason P.} and Neely, {Robert K.} and Yuval Ebenstein and Tegenfeldt, {Jonas O.}",
year = "2016",
language = "אנגלית",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "1527--1528",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}