DNA binding and catalytic properties of positively charged corroles

Zoya Gershman*, Israel Goldberg, Zeev Gross

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


DNA likes corroles and peroxynitrite doesn't: The water-soluble manganese corrole (crystal structure shown) is a much better catalyst than the analogous porphyrin for decomposition of peroxynitrite (HOONO). The interactions of the two complexes with DNA are also significantly different. These findings suggest that positively charged corroles may be useful for therapeutic approaches. (Figure Presented)

Original languageEnglish
Pages (from-to)4320-4324
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number23
StatePublished - 24 Mar 2007


  • Corroles
  • DNA
  • Manganese
  • Peroxynitrite
  • Porphyrinoids
  • Structure elucidation


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