Divalent Cation Levels in Serum and Preovulatory Follicular Fluid of Women Undergoing in vitro Fertilization Embryo Transfer

Foad Azem, Arik Hanannel, Yoram Wolf, Dalit Ben-Yosef, Israel Wagman, Israel Yovel, Rita Kapustiansky, Joseph B. Lessing, Mira Maclov, Ami Amit

Research output: Contribution to journalArticlepeer-review

Abstract

In this controlled clinical study, we determined the serum and follicular fluid concentrations of the biologically active fractions of magnesium (Mg) and calcium (Ca) in 39 women undergoing controlled ovarian stimulation (COH) for in vitro fertilization (IVF) embryo transfer (ET). Serum levels of ionized Ca (Ca2+) and ionized Mg (Mg2+) were measured during day 3 of the IVF cycle, on the day of ovum pickup and 12 days following ET. Follicular fluid levels were measured on the day of ovum pickup. Serum levels of Mg2+ decreased and Ca2+ levels increased during the IVF cycle. Mg levels were significantly higher in follicular fluid than in serum. Ca2+ and Mg2+ may play a role in the preovulatory follicle, a possibility that warrants further study.

Original languageEnglish
Pages (from-to)86-89
Number of pages4
JournalGynecologic and Obstetric Investigation
Volume57
Issue number2
DOIs
StatePublished - 2004

Keywords

  • Ca/Mg ratio follicular fluid
  • In vitro fertilization
  • Ionized calcium
  • Ionized magnesium
  • Serum

Fingerprint

Dive into the research topics of 'Divalent Cation Levels in Serum and Preovulatory Follicular Fluid of Women Undergoing in vitro Fertilization Embryo Transfer'. Together they form a unique fingerprint.

Cite this