Distance measurements between manganese(ii) and nitroxide spin-labels by DEER determine a binding site of Mn2+ in the HP92 loop of ribosomal RNA

Ilia Kaminker, Morgan Bye, Natanel Mendelman, Kristmann Gislason, Snorri Th Sigurdsson, Daniella Goldfarb

Research output: Contribution to journalArticlepeer-review

Abstract

Mn2+ localization in hairpin 92 of the 23S ribosomal RNA (HP92) was obtained using W-band (95 GHz) DEER (double electron-electron resonance) distance measurements between the Mn2+ ion and nitroxide spin labels on the RNA. It was found to be preferably situated in the minor groove of the double strand region close to the HP92 loop.

Original languageEnglish
Pages (from-to)15098-15102
Number of pages5
JournalPhysical Chemistry Chemical Physics
Volume17
Issue number23
DOIs
StatePublished - 21 Jun 2015
Externally publishedYes

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