Disseminated dermatophytic pseudomycetoma caused by Microsporum species

Mariantonieta Tirado-González*, Elizabeth Ball, Angela Ruiz, Ysabel Rodriguez, Carmen Elena Goudet, Oksana Finkel, Haim Golan, Helena Martinez de Morentin, Hanna Sprecher, Eli Sprecher, Andrea Gat

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background Dermatophyte infection is almost exclusively a superficial cutaneous mycosis usually confined to the stratum corneum of nails and hairs of normal hosts. Deep cutaneous and subcutaneous infections due to dermatophytes are exceedingly rare and usually limited to immunosuppressed individuals. These infections remain chronic and persist in spite of treatment. Materials and methods We report two clinical cases of disseminated dermatophytic pseudomycetoma caused by Microsporum gypseum and Microsporum canis in immunosuppressed patients. Results Patient 1, in 2008, showed improvement with fluconazole, cephalothin, and terbinafine treatment for Microsporum gypseum. After suspension of the treatment, new lesions appeared and culture from material was positive. In 2009, she presented confluent papules and nodules forming plaques on her face and neck with the isolation of Microsporum canis. Clinical response to this treatment was poor. Patient 2 was affected by both tinea corporis due to Trichophyton rubrum and dermatophytic pseudomycetoma caused by Microsporum canis. The response to treatment was successful with oral itraconazole and local surgical excision. Conclusions It is important to recognize these atypical presentations of dermatophytic infections in immunosuppressed patients, which may warrant a more aggressive treatment in order to achieve resolution.

Original languageEnglish
Pages (from-to)1478-1482
Number of pages5
JournalInternational Journal of Dermatology
Issue number12
StatePublished - Dec 2012
Externally publishedYes


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