Disappearance of diffuse calcinosis following autologous stem cell transplantation in a child with autoimmune disease

R. Elhasid*, J. M. Rowe, D. Berkowitz, M. Ben-Arush, R. Bar-Shalom, R. Brik

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

A 12 year-old girl presented with arthritis, myalgia, anemia and positive ANA. Subsequently, she developed recurrent episodes of pulmonary hemorrhage, thrombo-cytopenia, CNS abnormalities, skin ulcers and diffuse calcinosis. This was followed by secondary antiphospholipid syndrome. Despite vigorous immunosuppression, the patient became bedridden. A peripheral blood stem cell autograft was offered when she developed pulmonary hypertension and digital ischemia at the age of 16 years. The post-transplantation course was uneventful. Liquefaction of calcinosis nodules with improvement of mobility occurred gradually. She is now 24 months post-transplant with no sign of disease activity and total disappearance of calcinosis nodules.

Original languageEnglish
Pages (from-to)1257-1259
Number of pages3
JournalBone Marrow Transplantation
Volume33
Issue number12
DOIs
StatePublished - Jun 2004
Externally publishedYes

Keywords

  • Diffuse calcinosis
  • Peripheral blood stem cell transplantation (PBSCT)
  • T-cell depletion

Fingerprint

Dive into the research topics of 'Disappearance of diffuse calcinosis following autologous stem cell transplantation in a child with autoimmune disease'. Together they form a unique fingerprint.

Cite this