DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION.

Abel Ulrich; Gazit Ehud; Amir Yaniv; Buzhansky Ludmila; Frydman-Marom Anat

DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION.

Abel Ulrich (Inventor), Gazit Ehud (Inventor), Amir Yaniv (Inventor), Buzhansky Ludmila (Inventor), Frydman-Marom Anat (Inventor)

Biotechnology

RAMOT at Tel Aviv University LTD

Research output: Patent

Abstract

Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The didpeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the didpetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.

Original language	American English
Patent number	MX2013005413
IPC	A61P 25/ 28 A I
Priority date	15/11/11
State	Published - 27 Feb 2014

Cite this

@misc{409e45c83ad84cf2809e7069c167f679,

title = "DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION.",

abstract = "Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The didpeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the didpetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.",

author = "Abel Ulrich and Gazit Ehud and Amir Yaniv and Buzhansky Ludmila and Frydman-Marom Anat",

year = "2014",

month = feb,

day = "27",

language = "American English",

type = "Patent",

note = "MX2013005413; A61P 25/ 28 A I",

}

TY - PAT

T1 - DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION.

AU - Ulrich, Abel

AU - Ehud, Gazit

AU - Yaniv, Amir

AU - Ludmila, Buzhansky

AU - Anat, Frydman-Marom

PY - 2014/2/27

Y1 - 2014/2/27

N2 - Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The didpeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the didpetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.

AB - Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The didpeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the didpetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.

M3 - Patent

M1 - MX2013005413

ER -

DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION.

Abstract

Fingerprint

Cite this