Diffused coronary involvement in Takayasu arteritis with concomitant malignancy

Inbar Nardi-Agmon*, Ashraf Hamdan, Alon Eisen, Katia Orvin, Avital Porter, Hana Vaknin-Assa, Gilad Itchaki, Yair Molad, Ran Kornowski, Osnat Itzhaki Ben Zadok

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Large vessel vasculitis (LVV) is composed of conditions in which inflammation of blood vessel walls affects mainly large arteries, such as the aorta and its main branches, and in some cases the coronary arteries. Coronary artery involvement in systemic vasculitis is associated with significant morbidity and mortality. We present a case of a young patient diagnosed with extensive coronary disease diagnosed as Takayasu arteritis, when whom a concomitant diagnosis of Hodgkin’s lymphoma was made. The literature review revealed ten cases of malignancies associated with Takayasu arteritis. We discuss the complexity of the management of concurrent hematological malignancy with TAK and extensive coronary arteritis. This complicated and cross-disciplinary case also represents the pivotal importance of multi-disciplinary team decision in order to achieve the best clinical outcome of both disorders.

Original languageEnglish
Pages (from-to)921-928
Number of pages8
JournalClinical Rheumatology
Issue number3
StatePublished - Mar 2022


  • Coronary artery disease
  • Malignancy and large vessel vasculitis
  • Takayasu arteritis


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