Diffuse angiomatosis with hypersplenism. Splenectomy followed by polycythemia

Jack Pinkhas*, Meir Djaldetti, Andre de Vries, Doris Safra, Leah Dollberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A patient with diffuse hemangiomatosis involving the spleen, liver, skin and conjunctivas, with pancytopenia due to hypersplenism, is described. Additional abnormalities were a mitral valve lesion, localized electroencephalographic disturbance and typical abortive coloboma of the retina. Splenectomy resulted in normalization of blood cell counts followed by polycythemia. The etiology of the combined congenital anomalies and of the postsplenectomy polycythemia is discussed.

Original languageEnglish
Pages (from-to)795-801
Number of pages7
JournalAmerican Journal of Medicine
Issue number5
StatePublished - Nov 1968


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