Differentiation of pluripotent stem cells to skeletal muscle for cultivated meat applications

Michelle Hauser; Iftach Nachman; Gaya Savyon

doi:10.1016/B978-0-443-18767-4.00031-7

Differentiation of pluripotent stem cells to skeletal muscle for cultivated meat applications

Michelle Hauser, Iftach Nachman, Gaya Savyon

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

In this chapter, we provide an overview of the various strategies for differentiating pluripotent stem cells into skeletal muscle, the main tissue type in meat. We discuss the challenges and opportunities regarding efficiency and costs they arise in the different parameters of cultivated meat production bioprocess: 2D versus 3D cultivation and directed differentiation versus direct reprogramming differentiation methods. We examine the various factors that need to be considered when selecting a particular differentiation strategy for cultivated meat production.

Original language	English
Title of host publication	Cellular Agriculture
Subtitle of host publication	Technology, Society, Sustainability and Science
Publisher	Elsevier
Pages	203-214
Number of pages	12
ISBN (Electronic)	9780443187674
ISBN (Print)	9780443187667
DOIs	https://doi.org/10.1016/B978-0-443-18767-4.00031-7
State	Published - 1 Jan 2023

Keywords

Cultivated meat bioprocess
Differentiation
Myogenesis
Pluripotent stem cells
Skeletal muscle
Skeletal muscle organoid

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10.1016/B978-0-443-18767-4.00031-7

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Differentiation of pluripotent stem cells to skeletal muscle for cultivated meat applications

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Keywords

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