Different effects of the polysaccharide levan on the oncogenicity of cells of two variants of Lewis lung carcinoma

Y. Stark, J. Leibovici

Research output: Contribution to journalArticlepeer-review

Abstract

A marked difference in sensitivity to the direct effect of the polysaccharide levan on tumour cells was observed between two variants of malignancy of Lewis lung carcinoma: cells of the more malignant variant (3LL-M) were much more sensitive to the drug than those of the less malignant tumour (3LL). A gradual decrease in tumorigenicity following preincubation with increasing levan concentrations was observed with both variants, but statistically significant inhibition was observed at lower levan concentrations with 3LL-M than with 3LL.

Original languageEnglish
Pages (from-to)141-147
Number of pages7
JournalBritish Journal of Experimental Pathology
Volume67
Issue number1
StatePublished - 1986

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