Diagnosis and classification of adult Still's disease

Naim Mahroum, Hussein Mahagna, Howard Amital

Research output: Contribution to journalArticlepeer-review


The cornerstone of adult onset Still's disease is the triad of daily fever, arthritis and rash. This syndrome remains enigmatic and most often a disease of exclusion. There are both musculoskeletal as well as systemic features. More importantly, reactive hemophagocytic syndrome may occur in patients. In this review we attempt to place this syndrome in perspective, including data on geoepidemiology, clinical and laboratory features.

Original languageEnglish
Pages (from-to)34-37
Number of pages4
JournalJournal of Autoimmunity
StatePublished - 2014


  • Arthritis
  • Cytokines
  • Fever
  • Fever of unknown origin
  • Rash
  • Still's disease


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