TY - JOUR
T1 - Diabetes mellitus predicts cognitive impairment in patients with ischemic stroke
AU - Mizrahi, Eliyahu Hayim
AU - Waitzman, Ana
AU - Blumstein, Tzvia
AU - Arad, Marina
AU - Adunsky, Abraham
PY - 2010/6
Y1 - 2010/6
N2 - Background: Non-insulin-dependent diabetes mellitus (NIDDM) is associated with an increased incidence of cognitive impairment. Methods: A retrospective chart review study involving 707 patients admitted for rehabilitation after an ischemic stroke. Cognitive status was assessed by the Mini-Mental State Examination (MMSE), and scores lower than 24 points were considered suggestive of cogn tive impairment. Results: Age, gender, NIDDM, dementia, and previous stroke emerged as the only statistically significant parameters differing between those with MMSE score lower than 24 or higher. After adjusting for confounding variables, NIDDM (odds ratio 1.46, 95% CI 1.05-2.05, P =.02) was associated with an increased risk of cognitive impairment. Conclusions: Our findings suggest that NIDDM is independently associated with lower MMSE scores in ischemic stroke patients. It identifies individuals in need of specifically targeted interventions and may assist in selecting and developing resources for cognitively impaired diabetic patients.
AB - Background: Non-insulin-dependent diabetes mellitus (NIDDM) is associated with an increased incidence of cognitive impairment. Methods: A retrospective chart review study involving 707 patients admitted for rehabilitation after an ischemic stroke. Cognitive status was assessed by the Mini-Mental State Examination (MMSE), and scores lower than 24 points were considered suggestive of cogn tive impairment. Results: Age, gender, NIDDM, dementia, and previous stroke emerged as the only statistically significant parameters differing between those with MMSE score lower than 24 or higher. After adjusting for confounding variables, NIDDM (odds ratio 1.46, 95% CI 1.05-2.05, P =.02) was associated with an increased risk of cognitive impairment. Conclusions: Our findings suggest that NIDDM is independently associated with lower MMSE scores in ischemic stroke patients. It identifies individuals in need of specifically targeted interventions and may assist in selecting and developing resources for cognitively impaired diabetic patients.
KW - Cognitive impairment
KW - Diabetes mellitus
KW - Ischemic stroke
KW - Vascular risk factors
UR - http://www.scopus.com/inward/record.url?scp=77953637531&partnerID=8YFLogxK
U2 - 10.1177/1533317510365343
DO - 10.1177/1533317510365343
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:77953637531
SN - 1533-3175
VL - 25
SP - 362
EP - 366
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
IS - 4
ER -
