TY - JOUR
T1 - Dexamethasone in Cerebral Malaria
AU - Hall, Anthony
AU - Macpherson, D. W.
AU - Hoffman, Stephen L.
AU - Naparstek, Y.
AU - Weiler-Ravell, D.
AU - Shemer, J.
AU - Englehard, D.
AU - Sack, J.
AU - Adler, J.
AU - Warrell, David A.
AU - Looareesuwan, Sornchai
AU - Warrell, M. J.
AU - Bunnag, Danai
AU - Harinasuta, Tranakchit
PY - 1982/7/29
Y1 - 1982/7/29
N2 - To the Editor: I congratulate Warrell et al. (February 11 issue) for their important controlled study of coma due to falciparum malaria, which showed that dexamethasone increased the duration of coma and the incidence of complications.1 The low overall fatality rate of 17 per cent is noteworthy and a reflection of the quality of treatment. The authors did not state how many patients became comatose after entering the hospital and after receiving treatment with intravenous infusions of quinine. Quinine can cause coma,2 and as can fluid overload2 (possibly because of cerebral edema) and pulmonary edema; the latter developed in 10.
AB - To the Editor: I congratulate Warrell et al. (February 11 issue) for their important controlled study of coma due to falciparum malaria, which showed that dexamethasone increased the duration of coma and the incidence of complications.1 The low overall fatality rate of 17 per cent is noteworthy and a reflection of the quality of treatment. The authors did not state how many patients became comatose after entering the hospital and after receiving treatment with intravenous infusions of quinine. Quinine can cause coma,2 and as can fluid overload2 (possibly because of cerebral edema) and pulmonary edema; the latter developed in 10.
UR - http://www.scopus.com/inward/record.url?scp=0019965613&partnerID=8YFLogxK
U2 - 10.1056/NEJM198207293070518
DO - 10.1056/NEJM198207293070518
M3 - מזכר
C2 - 7088093
AN - SCOPUS:0019965613
VL - 307
SP - 317
EP - 319
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 5
ER -
