Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): A follow-up study

M. H. Ultmann*, G. W. Diamond, H. A. Ruff, A. L. Belman, B. E. Novick, A. Rubinstein, H. J. Cohen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Developmental abnormalities in 16 pediatric patients with AIDS or AIDS-Related Complex (ARC) were previously described. Neurological deterioration was in evidence on follow-up in 9 of the children, 5 died since the original assessments were performed. Ten patients were reevaluated 14 months later by cognitive testing. Two showed greater progress than expected on the basis of earlier test results; 6 showed the expected level of developmental progress; and the remaining 2 showed regression in cognitive functioning. All patients who exhibited regression in their developmental course showed deterioration in their neurological examinations. Developmental progression was noted in some children who on follow-up serial examinations exhibited a clinically deteriorating neurological picture. Pediatric AIDS patients manifest variable neurodevelopmental courses. As a result, rehabilitative intervention services must be tailored to meet individual needs.

Original languageEnglish
Pages (from-to)661-667
Number of pages7
JournalInternational Journal of Neuroscience
Issue number3-4
StatePublished - 1987
Externally publishedYes


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