Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): A follow-up study

M. H. Ultmann; G. W. Diamond; H. A. Ruff; A. L. Belman; B. E. Novick; A. Rubinstein; H. J. Cohen

doi:10.3109/00207458709043320

Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): A follow-up study

M. H. Ultmann^*, G. W. Diamond, H. A. Ruff, A. L. Belman, B. E. Novick, A. Rubinstein, H. J. Cohen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Developmental abnormalities in 16 pediatric patients with AIDS or AIDS-Related Complex (ARC) were previously described. Neurological deterioration was in evidence on follow-up in 9 of the children, 5 died since the original assessments were performed. Ten patients were reevaluated 14 months later by cognitive testing. Two showed greater progress than expected on the basis of earlier test results; 6 showed the expected level of developmental progress; and the remaining 2 showed regression in cognitive functioning. All patients who exhibited regression in their developmental course showed deterioration in their neurological examinations. Developmental progression was noted in some children who on follow-up serial examinations exhibited a clinically deteriorating neurological picture. Pediatric AIDS patients manifest variable neurodevelopmental courses. As a result, rehabilitative intervention services must be tailored to meet individual needs.

Original language	English
Pages (from-to)	661-667
Number of pages	7
Journal	International Journal of Neuroscience
Volume	32
Issue number	3-4
DOIs	https://doi.org/10.3109/00207458709043320
State	Published - 1987
Externally published	Yes

Funding

Funders	Funder number
National Institutes of Health	1984-1985, 5T32HDO 7053
National Institutes of Health
U.S. Department of Health and Human Services
Maternal and Child Health Bureau	-000241-17-1, 1983-1984
Maternal and Child Health Bureau
Eunice Kennedy Shriver National Institute of Child Health and Human Development	T32HD007053
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Cerebral Palsy Alliance Research Foundation	CF 118-84, 118-85, 118-83
Cerebral Palsy Alliance Research Foundation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/00207458709043320

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title = "Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): A follow-up study",

abstract = "Developmental abnormalities in 16 pediatric patients with AIDS or AIDS-Related Complex (ARC) were previously described. Neurological deterioration was in evidence on follow-up in 9 of the children, 5 died since the original assessments were performed. Ten patients were reevaluated 14 months later by cognitive testing. Two showed greater progress than expected on the basis of earlier test results; 6 showed the expected level of developmental progress; and the remaining 2 showed regression in cognitive functioning. All patients who exhibited regression in their developmental course showed deterioration in their neurological examinations. Developmental progression was noted in some children who on follow-up serial examinations exhibited a clinically deteriorating neurological picture. Pediatric AIDS patients manifest variable neurodevelopmental courses. As a result, rehabilitative intervention services must be tailored to meet individual needs.",

author = "Ultmann, {M. H.} and Diamond, {G. W.} and Ruff, {H. A.} and Belman, {A. L.} and Novick, {B. E.} and A. Rubinstein and Cohen, {H. J.}",

note = "Funding Information: Gary W. Diamond, M.D., was supported, in part, by the United Cerebral Palsy Research and Educational Foundation, Clinical Fellowship in Pediatrics (grant #CF 118-85 (1)). Funding Information: Monica H. Ultmann, M.D., was supported, in part, by the United Cerebral Palsy Research and Educational Foundation, Clinical Fellowship in Pediatrics (grant #CF 118-83 and CF 118-84), Department of Health and Human Services, Division of Maternal and Child Health (1983-1984) (grant #MCJ-000241-17-1), and the National Institutes of Health, Human Developmental Biology Training Grant (1984-1985) (grant #5T32HDO 7053).",

year = "1987",

doi = "10.3109/00207458709043320",

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AU - Belman, A. L.

AU - Novick, B. E.

AU - Rubinstein, A.

AU - Cohen, H. J.

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AB - Developmental abnormalities in 16 pediatric patients with AIDS or AIDS-Related Complex (ARC) were previously described. Neurological deterioration was in evidence on follow-up in 9 of the children, 5 died since the original assessments were performed. Ten patients were reevaluated 14 months later by cognitive testing. Two showed greater progress than expected on the basis of earlier test results; 6 showed the expected level of developmental progress; and the remaining 2 showed regression in cognitive functioning. All patients who exhibited regression in their developmental course showed deterioration in their neurological examinations. Developmental progression was noted in some children who on follow-up serial examinations exhibited a clinically deteriorating neurological picture. Pediatric AIDS patients manifest variable neurodevelopmental courses. As a result, rehabilitative intervention services must be tailored to meet individual needs.

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Developmental abnormalities in children with acquired immunodeficiency syndrome (AIDS): A follow-up study

Abstract

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UN SDGs

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