TY - JOUR
T1 - Determination of blood gases in children with extreme leukocytosis
AU - Shohat, M.
AU - Schonfeld, T.
AU - Zaizoz, R.
AU - Cohen, I. J.
AU - Nitzan, M.
PY - 1988
Y1 - 1988
N2 - The effect of extreme leukocytosis (>300,000/mm3) on the PaO2 of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO2 levels in the same range. One minute after drawing the samples, the PaO2 values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO2 values in both samples stored at 2° and 22°C. Rapid consumption of O2 by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.
AB - The effect of extreme leukocytosis (>300,000/mm3) on the PaO2 of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO2 levels in the same range. One minute after drawing the samples, the PaO2 values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO2 values in both samples stored at 2° and 22°C. Rapid consumption of O2 by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.
UR - http://www.scopus.com/inward/record.url?scp=0023789246&partnerID=8YFLogxK
U2 - 10.1097/00003246-198808000-00011
DO - 10.1097/00003246-198808000-00011
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AN - SCOPUS:0023789246
SN - 0090-3493
VL - 16
SP - 787
EP - 788
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 8
ER -
