Determination of blood gases in children with extreme leukocytosis

M. Shohat; T. Schonfeld; R. Zaizoz; I. J. Cohen; M. Nitzan

doi:10.1097/00003246-198808000-00011

Determination of blood gases in children with extreme leukocytosis

M. Shohat, T. Schonfeld, R. Zaizoz, I. J. Cohen, M. Nitzan

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Abstract

The effect of extreme leukocytosis (>300,000/mm³) on the PaO₂ of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO₂ levels in the same range. One minute after drawing the samples, the PaO₂ values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO₂ values in both samples stored at 2° and 22°C. Rapid consumption of O₂ by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.

Original language	English
Pages (from-to)	787-788
Number of pages	2
Journal	Critical Care Medicine
Volume	16
Issue number	8
DOIs	https://doi.org/10.1097/00003246-198808000-00011
State	Published - 1988
Externally published	Yes

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title = "Determination of blood gases in children with extreme leukocytosis",

abstract = "The effect of extreme leukocytosis (>300,000/mm3) on the PaO2 of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO2 levels in the same range. One minute after drawing the samples, the PaO2 values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO2 values in both samples stored at 2° and 22°C. Rapid consumption of O2 by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.",

author = "M. Shohat and T. Schonfeld and R. Zaizoz and Cohen, {I. J.} and M. Nitzan",

year = "1988",

doi = "10.1097/00003246-198808000-00011",

language = "אנגלית",

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journal = "Critical Care Medicine",

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T1 - Determination of blood gases in children with extreme leukocytosis

AU - Shohat, M.

AU - Schonfeld, T.

AU - Zaizoz, R.

AU - Cohen, I. J.

AU - Nitzan, M.

PY - 1988

Y1 - 1988

N2 - The effect of extreme leukocytosis (>300,000/mm3) on the PaO2 of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO2 levels in the same range. One minute after drawing the samples, the PaO2 values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO2 values in both samples stored at 2° and 22°C. Rapid consumption of O2 by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.

AB - The effect of extreme leukocytosis (>300,000/mm3) on the PaO2 of blood stored at 22° and 2°C was studied in two children with leukemia. Arterial blood samples drawn from these patients at 1 and 10 min were compared to blood samples drawn from eight control patients with normal leukocyte counts and PaO2 levels in the same range. One minute after drawing the samples, the PaO2 values at 2°C were significantly higher than those stored at 22°C. Later, there was a rapid and progressive decline in PaO2 values in both samples stored at 2° and 22°C. Rapid consumption of O2 by leukocytes is liable to result in erroneous diagnosis of severe hypoxemia in patients with extreme leukocytosis. Immediate cooling of the samples is insufficient to eliminate this process.

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DO - 10.1097/00003246-198808000-00011

M3 - מאמר

AN - SCOPUS:0023789246

VL - 16

SP - 787

EP - 788

JO - Critical Care Medicine

JF - Critical Care Medicine

SN - 0090-3493

IS - 8

ER -

Determination of blood gases in children with extreme leukocytosis

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