@inproceedings{fbcc13ee8ddd43ecb799794fb4c4aa11,
title = "Design of a method for prediction of susceptibility to antimicrobials",
abstract = "The results from the in vitro susceptibility tests are usually available only for a limited set of antibiotics. This paper provides a practical method for prediction of a posteriori probability for coverage for all relevant antibiotics. The method combines susceptibility results for a limited set of antibiotics with data on cross-resistance between antibiotics. The Brier distance was used to measure the accuracy of the predicted coverages. Across all pathogen/antibiotic combinations in the derivation database, the Brier distances for a priori coverages was 39%, reduced to 25% for predicted a posteriori coverages, indicating that there is a significant advantage to the method proposed (p<10 -99).",
keywords = "A posteriori probability, Antibiotic therapy, Bacterial infections, Cross-resistance, Susceptibility test",
author = "Steen Andreassen and Alina Zalounina and Mical Paul and Leonard Leibovici",
year = "2009",
doi = "10.3182/20090812-3-DK-2006.0064",
language = "אנגלית",
isbn = "9783902661494",
series = "IFAC Proceedings Volumes (IFAC-PapersOnline)",
publisher = "IFAC Secretariat",
number = "PART 1",
pages = "313--318",
booktitle = "7th IFAC Symposium on Modelling and Control in Biomedical Systems (including Biological Systems) MCBMS'09 - Proceedings",
address = "אוסטריה",
edition = "PART 1",
}