DERIVATIZED NYLON: A NEW SUPPORT FOR THE IMMOBILIZATION OF ENZYMES.

L. Goldstein, A. Freeman, M. Sokolovsky

Research output: Contribution to conferencePaperpeer-review

Abstract

The interest in nylon and related polyamides as possible supports for the covalent attachment of enzymes stems from their high stability and relatively low cost. However, they suffer from a serious drawback in that only the terminal carboxyl and amino groups can be utilized for the covalent binding of proteins. Procedures by which the binding capacity of nylon could be increased by mild acid hydrolysis have been described recently by Hornby et al. This communication describes a method for introducing chemically reactive groups onto the nylon backbone, without causing a decrease in the mol. wt and thus impairing the mechanical properties of the final product. Details of the experimental study are presented in which various enzymes were mobilized on supports of various polyamides and their derivatives.

Original languageEnglish
Pages97-104
Number of pages8
DOIs
StatePublished - 1974
EventEng Found Conf on Enzyme Eng, 2nd, Proc - Henniker, NH, USA
Duration: 5 Aug 197310 Aug 1973

Conference

ConferenceEng Found Conf on Enzyme Eng, 2nd, Proc
CityHenniker, NH, USA
Period5/08/7310/08/73

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