Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: A 1-year retrospective study

Zvi Artzi, Haim Tal, Ori Platner, Nadav Wasersprung, Weinberg Evgeny, Shimshon Slutzkey, Nir Gozali, Guy Carmeli, Ran Herzberg, Avital Kozlovsky

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Objectives To retrospectively evaluate and compare two regenerative periodontal procedures in young individuals with aggressive periodontitis (AgP). Methods Thirty-two patients aged 14-25 years (mean ± SD 19.3 ± 5.7) were diagnosed as having AgP with multiple intra-bony defects (IBDs) and treated by one of two regenerative modalities of periodontal therapy: guided tissue regeneration (GTR) using deproteinized bone xenograft (DBX) particles and a resorbable membrane (the GTR group), or an application of enamel matrix derivatives (EMD) combined with DBX (the EMD/DBX group). Periodic monitoring of treated sites included recording of probing depth (PD), clinical attachment level (CAL) and gingival recession. Pre-treatment and 1-year post-operative findings were statistically analysed within and between groups. Results The PD and CAL values decreased significantly with time, but not those between study groups. The mean pre-treatment and 1-year post-treatment PDs of the IBDs of the GTR group (n = 16; sites = 67) were 8.93 ± 1.14 mm and 3.58 ± 0.50 mm, respectively, and the mean CALs were 9.03 ± 1.03 mm and 4.16 ± 0.53 mm respectively. The mean PDs of the EMD/DBX group (n = 16; sites = 73) were 8.77 ± 1.04 mm and 3.61 ± 0.36 mm, respectively, and the mean CALS were 8.79 ± 1.04 mm and 3.77 ± 0.22 mm respectively (p < 0.001 for all). Conclusion Surgical treatment of AgP patients by either GTR or by application of EMD/DBX yielded similarly successful clinical results at 1-year post-treatment.

Original languageEnglish
Pages (from-to)547-556
Number of pages10
JournalJournal of Clinical Periodontology
Volume42
Issue number6
DOIs
StatePublished - 1 Jun 2015

Keywords

  • Aggressive periodontitis
  • deproteinized bovine bone (Bio-Oss®)
  • enamel matrix derivatives (Emdogain®)
  • guided tissue regeneration
  • periodontal regeneration

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