Deoxyribonucleic acid-damaged sperm in cryopreserved-thawed specimens from cancer patients and healthy men

Avital Edelstein, Haim Yavetz, Sandra E. Kleiman, Amnon Botchan, Ron Hauser, Gedalia Paz, Leah Yogev

Research output: Contribution to journalArticlepeer-review

Abstract

A similarity was found between the percentage of thawed, DNA-damaged spermatozoa in cancer patients and that in candidates to become sperm bank donors who had low sperm cryofreezability. Both groups were significantly different from the sperm bank donor group. It is suggested that the higher rate of DNA fragmentation in sperm from cancer patients compared with sperm bank donors is apparently a result of selecting donors by the level of sperm cryofreezability (i.e., high), rather than a direct effect of an existing malignancy.

Original languageEnglish
Pages (from-to)205-208
Number of pages4
JournalFertility and Sterility
Volume90
Issue number1
DOIs
StatePublished - Jul 2008
Externally publishedYes

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