Deoxyribonucleases of the Oriental hornet (Vespa orientalis) venom-II. Partial characterization and effects in vivo on insects and mammals

B. Ring; H. Slor; B. Perna; J. S. Ishay

doi:10.1016/0041-0101(78)90144-7

Deoxyribonucleases of the Oriental hornet (Vespa orientalis) venom-II. Partial characterization and effects in vivo on insects and mammals

B. Ring^*, H. Slor, B. Perna, J. S. Ishay

^*Corresponding author for this work

NY American Medicine Program

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The presence of DNases in Oriental hornet venom sac extract and venom glands and their activity on invertebrates (bees) and vertebrates (mice and cats) were assessed. It was found that the DNase activity is greatest at neutral pH in the venom sacs and in the acid glands, with very little activity being demonstrated in the alkaline gland. Queen hornets showed greater DNase activity in their acid glands than in their sacs. Workers, on the other hand, showed greater activity in the venom sacs than in the glands. Bees, mice and cats, when injected with hornet venom, showed an increase in nucleic acids, but the onset of the appearance of the DNA degradation products varied with the species: in bees after 5 min, in mice after 7 hr and in cats after 24 hr.

Original language	English
Pages (from-to)	473-478
Number of pages	6
Journal	Toxicon
Volume	16
Issue number	5
DOIs	https://doi.org/10.1016/0041-0101(78)90144-7
State	Published - 1978

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abstract = "The presence of DNases in Oriental hornet venom sac extract and venom glands and their activity on invertebrates (bees) and vertebrates (mice and cats) were assessed. It was found that the DNase activity is greatest at neutral pH in the venom sacs and in the acid glands, with very little activity being demonstrated in the alkaline gland. Queen hornets showed greater DNase activity in their acid glands than in their sacs. Workers, on the other hand, showed greater activity in the venom sacs than in the glands. Bees, mice and cats, when injected with hornet venom, showed an increase in nucleic acids, but the onset of the appearance of the DNA degradation products varied with the species: in bees after 5 min, in mice after 7 hr and in cats after 24 hr.",

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AU - Perna, B.

AU - Ishay, J. S.

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Deoxyribonucleases of the Oriental hornet (Vespa orientalis) venom-II. Partial characterization and effects in vivo on insects and mammals

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