Dendritic polyglycerol-poly(ethylene glycol)-based polymer networks for biosensing application

Pradip Dey; Miriam Adamovski; Simon Friebe; Artavazd Badalyan; Radu Cristian Mutihac; Florian Paulus; Silke Leimkühler; Ulla Wollenberger; Rainer Haag

doi:10.1021/am502018x

Dendritic polyglycerol-poly(ethylene glycol)-based polymer networks for biosensing application

Pradip Dey, Miriam Adamovski, Simon Friebe, Artavazd Badalyan, Radu Cristian Mutihac, Florian Paulus, Silke Leimkühler, Ulla Wollenberger^*, Rainer Haag

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

This work describes the formation of a new dendritic polyglycerol- poly(ethylene glycol)-based 3D polymer network as a matrix for immobilization of the redox enzyme periplasmatic aldehyde oxidoreductase to create an electrochemical biosensor. The novel network is built directly on the gold surface, where it simultaneously stabilizes the enzyme for up to 4 days. The prepared biosensors can be used for amperometric detection of benzaldehyde in the range of 0.8-400 μM.

Original language	English
Pages (from-to)	8937-8941
Number of pages	5
Journal	ACS Applied Materials and Interfaces
Volume	6
Issue number	12
DOIs	https://doi.org/10.1021/am502018x
State	Published - 25 Jun 2014
Externally published	Yes

Keywords

amperometry
biosensors
dendritic
hydrogel

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10.1021/am502018x

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abstract = "This work describes the formation of a new dendritic polyglycerol- poly(ethylene glycol)-based 3D polymer network as a matrix for immobilization of the redox enzyme periplasmatic aldehyde oxidoreductase to create an electrochemical biosensor. The novel network is built directly on the gold surface, where it simultaneously stabilizes the enzyme for up to 4 days. The prepared biosensors can be used for amperometric detection of benzaldehyde in the range of 0.8-400 μM.",

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AU - Adamovski, Miriam

AU - Friebe, Simon

AU - Badalyan, Artavazd

AU - Mutihac, Radu Cristian

AU - Paulus, Florian

AU - Leimkühler, Silke

AU - Wollenberger, Ulla

AU - Haag, Rainer

PY - 2014/6/25

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AB - This work describes the formation of a new dendritic polyglycerol- poly(ethylene glycol)-based 3D polymer network as a matrix for immobilization of the redox enzyme periplasmatic aldehyde oxidoreductase to create an electrochemical biosensor. The novel network is built directly on the gold surface, where it simultaneously stabilizes the enzyme for up to 4 days. The prepared biosensors can be used for amperometric detection of benzaldehyde in the range of 0.8-400 μM.

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KW - biosensors

KW - dendritic

KW - hydrogel

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Dendritic polyglycerol-poly(ethylene glycol)-based polymer networks for biosensing application

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Keywords

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