Demyelinating peripheral neuropathy in Creutzfeldt–Jakob disease

Miriam Y. Neufeld, Joseph Josiphov, Amos D. Korczyn*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


We desribe 2 patients of Jewish Libyan descent, who presented with a clinical syndrome compatible with Creutzfeldt–Jakob disease and who were found to have a mutation of codon 200 in the prion protein. The patients developed symptoms and signs of peripheral nerve involvement diagnosed by electrodiagnostic and histopathological studies as demyelinating neuropathy. This may be a rare manifestation of Creutzfeldt–Jakob disease. © 1992 John Wiley & Sons, Inc.

Original languageEnglish
Pages (from-to)1234-1239
Number of pages6
JournalMuscle and Nerve
Issue number11
StatePublished - Nov 1992


  • Creutzfeldt–Jakob disease
  • demyelinating neuropathy
  • peripheral neuropathy
  • peripheral neuropathy
  • prions


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