Deleterious effect of anti-insulin antibodies on diabetes control

A. Livneh, H. Avraham, T. Bistritzer, L. Weisglass, R. Theodor, J. Sack

Research output: Contribution to journalArticlepeer-review


We studied the effect of anti-insulin antibodies (AIA) on glycemia control in patients with insulin-dependent diabetes (IDD) by following the AIA titer changes with time. Although expected to remain constant, AIA levels were found to either increase or decrease in most patients. These AIA titer changes correlated significantly with changes in glycohemoglobin but not with changes in insulin dose. The results suggest that AIA may have a deleterious effect on glycemia control in IDD.

Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalIsrael Journal of Medical Sciences
Issue number1
StatePublished - 1990
Externally publishedYes


  • Anti-insulin antibodies
  • diabetes control
  • insulin-dependent diabetes


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