Deep vein thrombosis prevention in joint arthroplasties: Continuous enhanced circulation therapy vs low molecular weight heparin

Yael Gelfer, Hovav Tavor, Amir Oron, Amir Peer, Nahum Halperin, Dror Robinson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

Deep vein thrombosis prevention efficacy using a new, miniature, mobile, battery-operated pneumatic system (continuous enhanced circulation therapy [CECT] system) combined with low-dose aspirin was compared to enoxaparin. One hundred twenty-one patients who underwent total hip or knee arthroplasty were prospectively randomized into 2 groups. The study group was treated by the CECT system starting immediately after the induction of anesthesia. Postoperatively, a daily 100-mg aspirin tablet was added. The control group received 40 mg of enoxaparin per day. Bilateral venography was performed at the fifth to eight postoperative day. In the CECT group, as compared to the enoxaparin group, there was a significantly lower overall rate of DVT and proximal DVT. Safety profiles were similar in both groups. The combination of the CECT device with low-dose aspirin is more effective than enoxaparin in preventing deep-vein thrombosis after lower limb arthroplasties.

Original languageEnglish
Pages (from-to)206-214
Number of pages9
JournalJournal of Arthroplasty
Volume21
Issue number2
DOIs
StatePublished - Feb 2006

Keywords

  • Arthroplasty
  • Aspirin
  • Compliance
  • Continuous enhanced circulation therapy
  • Deep vein thrombosis
  • Intermittent pneumatic compression
  • Low molecular weight heparin
  • Total hip arthroplasty
  • Total knee arthroplasty

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