TY - JOUR
T1 - De novo purine synthesis in skeletal muscle
AU - Brosh, S.
AU - Boer, P.
AU - Zoref-Shani, E.
AU - Sperling, O.
PY - 1982/1/12
Y1 - 1982/1/12
N2 - Myoblast and primary muscle cultures from rat were found to contain the complete pathway of de novo purine nucleotide synthesis. Quantitative assessment of the pathway in skeletal muscle in mice in vivo, revealed a more intensive purine production in muscle than in liver. Skeletal muscle is thus a major site of de novo purine production in the mammalian body.
AB - Myoblast and primary muscle cultures from rat were found to contain the complete pathway of de novo purine nucleotide synthesis. Quantitative assessment of the pathway in skeletal muscle in mice in vivo, revealed a more intensive purine production in muscle than in liver. Skeletal muscle is thus a major site of de novo purine production in the mammalian body.
KW - Cell culture (Skeletal muscle)
KW - Purine nucleotide synthesis
UR - http://www.scopus.com/inward/record.url?scp=0020029006&partnerID=8YFLogxK
U2 - 10.1016/0304-4165(82)90143-X
DO - 10.1016/0304-4165(82)90143-X
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AN - SCOPUS:0020029006
SN - 0304-4165
VL - 714
SP - 181
EP - 183
JO - Biochimica et Biophysica Acta - General Subjects
JF - Biochimica et Biophysica Acta - General Subjects
IS - 1
ER -