Data comparing the kinetics of procollagen type I processing by bone morphogenetic protein 1 (BMP-1) with and without procollagen C-proteinase enhancer 1 (PCPE-1)

Laura Moschcovich, Efrat Kessler

Research output: Contribution to journalArticlepeer-review

Abstract

This article provides kinetic constants for C-terminal processing of procollagen type I by bone morphogenetic protein 1 (BMP-1; the major procollagen C-proteinase), a reaction stimulated by the connective tissue glycoprotein procollagen C-proteinase enhancer 1 (PCPE-1). Reported are Km, Vmax, Kcat and Kcat/Km (catalytic coefficient) values for BMP-1 alone, BMP-1 with intact PCPE-1, BMP-1 with the CUB (Complement C1r/C1s, Uegf, BMP-1) domains fragment of PCPE-1 as well as its NTR (netrin-like) domain.

Original languageEnglish
Pages (from-to)883-887
Number of pages5
JournalData in Brief
Volume9
DOIs
StatePublished - Dec 2016

Keywords

  • Bone morphogenetic protein 1
  • Collagen biology
  • Enzyme kinetics
  • Extracellular matrix
  • Procollagen C-proteinase
  • Procollagen C-proteinase enhancer
  • Proteolytic processing

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