Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Wared Alemu*, Michalis Xenos, Yuefan Deng, Rui Feng, Shmuel Einav, Danny Bluestein

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

Original languageEnglish
Title of host publicationProceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages1097-1098
Number of pages2
EditionPART B
StatePublished - 2009
Externally publishedYes
Event10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States
Duration: 25 Jun 200829 Jun 2008

Publication series

NameProceedings of the ASME Summer Bioengineering Conference, SBC2008
NumberPART B

Conference

Conference10th ASME Summer Bioengineering Conference, SBC2008
Country/TerritoryUnited States
CityMarco Island, FL
Period25/06/0829/06/08

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