Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Wared Alemu; Michalis Xenos; Yuefan Deng; Rui Feng; Shmuel Einav; Danny Bluestein

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Wared Alemu^*, Michalis Xenos, Yuefan Deng, Rui Feng, Shmuel Einav, Danny Bluestein

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

Original language	English
Title of host publication	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages	1097-1098
Number of pages	2
Edition	PART B
State	Published - 2009
Externally published	Yes
Event	10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States Duration: 25 Jun 2008 → 29 Jun 2008

Publication series

Name	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Number	PART B

Conference

Conference	10th ASME Summer Bioengineering Conference, SBC2008
Country/Territory	United States
City	Marco Island, FL
Period	25/06/08 → 29/06/08

Cite this

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title = "Damage accumulation model of prosthetic heart valves in forward and reverse flow phases",

abstract = "A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.",

author = "Wared Alemu and Michalis Xenos and Yuefan Deng and Rui Feng and Shmuel Einav and Danny Bluestein",

year = "2009",

language = "אנגלית",

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series = "Proceedings of the ASME Summer Bioengineering Conference, SBC2008",

number = "PART B",

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edition = "PART B",

note = "null ; Conference date: 25-06-2008 Through 29-06-2008",

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Alemu, W, Xenos, M, Deng, Y, Feng, R, Einav, S & Bluestein, D 2009, Damage accumulation model of prosthetic heart valves in forward and reverse flow phases. in Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B edn, Proceedings of the ASME Summer Bioengineering Conference, SBC2008, no. PART B, pp. 1097-1098, 10th ASME Summer Bioengineering Conference, SBC2008, Marco Island, FL, United States, 25/06/08.

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases. / Alemu, Wared; Xenos, Michalis; Deng, Yuefan et al.

Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B. ed. 2009. p. 1097-1098 (Proceedings of the ASME Summer Bioengineering Conference, SBC2008; No. PART B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

AU - Alemu, Wared

AU - Xenos, Michalis

AU - Deng, Yuefan

AU - Feng, Rui

AU - Einav, Shmuel

AU - Bluestein, Danny

PY - 2009

Y1 - 2009

N2 - A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

AB - A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

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M3 - פרסום בספר כנס

AN - SCOPUS:77952641174

SN - 9780791843215

T3 - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

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BT - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

Y2 - 25 June 2008 through 29 June 2008

ER -

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Abstract

Publication series

Conference

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