D-dimer and C-reactive protein blood levels over time used to predict pulmonary embolism in two covid-19 patients

Yael Becher; Leonid Goldman; Nadav Schacham; Irina Gringauz; Dan Justo

doi:10.12890/2020_001725

D-dimer and C-reactive protein blood levels over time used to predict pulmonary embolism in two covid-19 patients

Yael Becher, Leonid Goldman, Nadav Schacham, Irina Gringauz, Dan Justo

Internal Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.

Original language	English
Journal	European Journal of Case Reports in Internal Medicine
Volume	7
Issue number	6
DOIs	https://doi.org/10.12890/2020_001725
State	Published - 2020

Keywords

C-reactive protein
COVID-19
D-dimer
Pulmonary embolism

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10.12890/2020_001725

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abstract = "The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.",

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AU - Becher, Yael

AU - Goldman, Leonid

AU - Schacham, Nadav

AU - Gringauz, Irina

AU - Justo, Dan

N1 - Publisher Copyright: © EFIM 2020

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Y1 - 2020

N2 - The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.

AB - The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.

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D-dimer and C-reactive protein blood levels over time used to predict pulmonary embolism in two covid-19 patients

Abstract

Keywords

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