Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: A case report

Lihi Atzmony, Nili Saar, Tamar Chundadze, Yaron Arbel, Dan Justo, Noa Mashav

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Cytomegalovirus-associated thrombosis has rarely been reported in the medical literature, and if so, mainly in immunocompromized patients. Case presentation: We report the case of a 36-year-old Caucasian woman with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Trans-esophageal echocardiography did not show any vegetations or mural thrombi. The patient was also found to be heterozygous for the Factor V Leiden mutation. Anticoagulation treatment was considered but ruled out since cytomegalovirus was the obvious trigger for thrombosis in this patient. To the best of our knowledge, this is only the third report to date of cytomegalovirus-associated splenic infarcts. Conclusion: This case report serves as additional evidence for the role of cytomegalovirus in thrombosis.

Original languageEnglish
Article number385
JournalJournal of Medical Case Reports
Volume2
DOIs
StatePublished - 16 Dec 2008
Externally publishedYes

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