Cystectomy for immature teratoma of the ovary

Mario E. Beiner, Walter H. Gotlieb, Yaacov Korach, Alon Shrim, David Stockheim, Yaacov Segal, Eduard Fridman, Gilad Ben-Baruch*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objectives. Most patients with malignant ovarian germ cell tumors (MOGCT) of the ovary are in their reproductive years and wish to preserve fertility. Because of the excellent response to chemotherapy, the standard of care is unilateral salpingo-oophorectomy (USO), but some patients undergo cystectomy only before final pathology. In view of the lack of information concerning the outcome following cystectomy in germ cell tumors, we retrospectively evaluated the clinical outcome of patients who underwent cystectomy only as part of their surgical treatment. Methods. The clinical and pathological records of 38 patients diagnosed with MOGCT, treated and followed in the department of gynecologic oncology were reviewed. Eight patients underwent cystectomy only at their initial surgery and are the subjects of this study. Results. All the eight patients who underwent cystectomy were diagnosed with immature teratoma (three grade 1, four grade 2, and one grade 3) on final pathology following surgery. All except three patients (two with grade 1 and one with grade 2 disease) received adjuvant chemotherapy. Follow-up was available for all the patients, with a median duration of 4.7 years. No recurrences were observed during this period. Three patients delivered a total of seven babies. Conclusions. Cystectomy followed by adjuvant chemotherapy appeared satisfactory for apparent early-stage immature teratoma when close follow-up was carried out. It is still unclear whether cystectomy alone will also be safe. Further studies will need to address this issue.

Original languageEnglish
Pages (from-to)381-384
Number of pages4
JournalGynecologic Oncology
Issue number2
StatePublished - May 2004


  • Cystectomy
  • Germ cell tumors
  • Teratoma


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