Cyclosporin: Poorly Tolerated in Familial Mediterranean Fever

S. L. Cohen*, G. Boner, D. Shmueli, A. Yusim, J. Rosenfeld, Z. Shapira

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Cyclosporin is poorly tolerated in patients with amyloidosis due to familial mediterranean fever who are receiving colchicine. There is a high incidence of gastrointestinal side-effects and muscle weakness, both of which are reversible on stopping cyclosporin. Thus in patients with amyloidosis secondary to familial mediterranean fever treated with colchicine, the use of cyclosporin as an immunosuppressive agent may be restricted.

Original languageEnglish
Pages (from-to)201-204
Number of pages4
JournalNephrology Dialysis Transplantation
Issue number3
StatePublished - 1989


  • Amyloidosis
  • Colchicine
  • Cyclosporin intolerance
  • Familial mediterranean fever
  • Gastrointestinal upset
  • Muscle weakness


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