TY - JOUR
T1 - Cyanthiwigin A-D, novel cytotoxic diterpenes from the sponge epipolasis reiswigi
AU - Green, D.
AU - Goldberg, I.
AU - Stein, Z.
AU - Ilan, M.
AU - Kashman, Y.
PY - 1992/11
Y1 - 1992/11
N2 - Four novel diterpenes, cyanthiwigin A-D (1-4) have been isolated from the marine sponge E. reiswigi and their structure elucidated by mass and mainly NMR spectra. The tricarbocyclic structure of I was confirmed by an X-ray analysis and its absolute configuration was established to be 4S, 5R, 6S, 9S by the modified Mosher's method. The four compounds have the same planar skeleton as cyanthin but differ in their stereochemistry. Key Words: Diterpenoids, X-ray, Absolute configuration, NMR.
AB - Four novel diterpenes, cyanthiwigin A-D (1-4) have been isolated from the marine sponge E. reiswigi and their structure elucidated by mass and mainly NMR spectra. The tricarbocyclic structure of I was confirmed by an X-ray analysis and its absolute configuration was established to be 4S, 5R, 6S, 9S by the modified Mosher's method. The four compounds have the same planar skeleton as cyanthin but differ in their stereochemistry. Key Words: Diterpenoids, X-ray, Absolute configuration, NMR.
KW - Absolute configuration
KW - Diterpenoids
KW - NMR
KW - X-ray
UR - http://www.scopus.com/inward/record.url?scp=0000291683&partnerID=8YFLogxK
U2 - 10.1080/10575639208048911
DO - 10.1080/10575639208048911
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AN - SCOPUS:0000291683
SN - 1057-5634
VL - 1
SP - 193
EP - 199
JO - Natural Product Letters
JF - Natural Product Letters
IS - 3
ER -