Current debate on the use of antibiotic prophylaxis for caesarean section

R. F. Lamont, J. D. Sobel, J. P. Kusanovic, E. Vaisbuch, S. Mazaki-Tovi, S. K. Kim, N. Uldbjerg, R. Romero

Research output: Contribution to journalReview articlepeer-review

Abstract

Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tract infection. Most surgical site infections occur after discharge from the hospital, and are increasingly being used as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidence-based guidelines recommended the use of prophylactic antibiotics before surgical incision. An exception is made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision, broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage to the neonate.

Original languageEnglish
Pages (from-to)193-201
Number of pages9
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Volume118
Issue number2
DOIs
StatePublished - Jan 2011
Externally publishedYes

Keywords

  • Antibiotics
  • caesarean section
  • endometritis
  • pregnancy
  • prophylaxis
  • surgical site infections

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