TY - JOUR
T1 - CT and MRI in late‐onset metachromatic leukodystrophy
AU - Reider‐Grosswasser, I.
AU - Bornstein, N.
PY - 1987/1
Y1 - 1987/1
N2 - ABSTRACT— A 23‐year‐old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13‐year‐old retarded sister. The diagnosis of metachromatic leukodystrophy (MLD) was confirmed by the finding of low arylsulfatase A (ASA) levels in cultured fibroblasts in both sisters. MRI study revealed widespread high intensity signals of T2 nature in the periventricular regions indicating changes in white matter composition.
AB - ABSTRACT— A 23‐year‐old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13‐year‐old retarded sister. The diagnosis of metachromatic leukodystrophy (MLD) was confirmed by the finding of low arylsulfatase A (ASA) levels in cultured fibroblasts in both sisters. MRI study revealed widespread high intensity signals of T2 nature in the periventricular regions indicating changes in white matter composition.
KW - CT
KW - MRI
KW - metachromatic leukodystrophy
UR - http://www.scopus.com/inward/record.url?scp=0023153545&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0404.1987.tb07891.x
DO - 10.1111/j.1600-0404.1987.tb07891.x
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AN - SCOPUS:0023153545
SN - 0001-6314
VL - 75
SP - 64
EP - 69
JO - Acta Neurologica Scandinavica
JF - Acta Neurologica Scandinavica
IS - 1
ER -