Csn5a subunit of cop9 signalosome is required for resetting transcriptional stress memory after recurrent heat stress in arabidopsis

Amit Kumar Singh, Shanmuhapreya Dhanapal, Alin Finkelshtein, Daniel A. Chamovitz

Research output: Contribution to journalArticlepeer-review

Abstract

In nature, plants are exposed to several environmental stresses that can be continuous or recurring. Continuous stress can be lethal, but stress after priming can increase the tolerance of a plant to better prepare for future stresses. Reports have suggested that transcription factors are involved in stress memory after recurrent stress; however, less is known about the factors that regulate the resetting of stress memory. Here, we uncovered a role for Constitutive Photomorphogenesis 5A (CSN5A) in the regulation of stress memory for resetting transcriptional memory genes (APX2 and HSP22) and H3K4me3 following recurrent heat stress. Furthermore, CSN5A is also required for the deposition of H3K4me3 following recurrent heat stress. Thus, CSN5A plays an important role in the regulation of histone methylation and transcriptional stress memory after recurrent heat stress.

Original languageEnglish
Article number668
JournalBiomolecules
Volume11
Issue number5
DOIs
StatePublished - May 2021

Keywords

  • COP9 signalosome
  • Histone methylation
  • Hypomorphic mutant
  • Recurrent heat stress
  • Transcriptional stress memory

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