TY - JOUR
T1 - Cross resistance to ciprofloxacin and other antimicrobial agents among clinical isolates of Acinetobacter calcoaceticus biovar anitratus
AU - Shalit, I.
AU - Dan, M.
AU - Gutman, R.
AU - Gorea, A.
AU - Berger, S. A.
PY - 1990
Y1 - 1990
N2 - Using an agar dilution assay, for 66 of 104 (63.5%) clinical isolates of Acinetobacter calcoaceticus biovar anitratus, the MIC of ciprofloxacin was ≥ 1.0 μg/ml. Cross resistance was demonstrable to ciprofloxacin and gentamicin (P < 0.001), amikacin (P < 0.01), cefotaxime (P < 0.001), azlocillin (P < 0.001), ceftazidime (P < 0.001), trimethoprim-sulfamethoxazole (P < 0.001), and minocycline (P < 0.05). The mean MIC of ciprofloxacin for drug-susceptible isolates was consistently lower than that for resistant isolates; however, these differences were significant only for amikacin (P = 0.036).
AB - Using an agar dilution assay, for 66 of 104 (63.5%) clinical isolates of Acinetobacter calcoaceticus biovar anitratus, the MIC of ciprofloxacin was ≥ 1.0 μg/ml. Cross resistance was demonstrable to ciprofloxacin and gentamicin (P < 0.001), amikacin (P < 0.01), cefotaxime (P < 0.001), azlocillin (P < 0.001), ceftazidime (P < 0.001), trimethoprim-sulfamethoxazole (P < 0.001), and minocycline (P < 0.05). The mean MIC of ciprofloxacin for drug-susceptible isolates was consistently lower than that for resistant isolates; however, these differences were significant only for amikacin (P = 0.036).
UR - http://www.scopus.com/inward/record.url?scp=0025138308&partnerID=8YFLogxK
U2 - 10.1128/AAC.34.3.494
DO - 10.1128/AAC.34.3.494
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AN - SCOPUS:0025138308
VL - 34
SP - 494
EP - 495
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 3
ER -
