COVID-19 and Autoimmunity

Prashant S. Giri; Shahnawaz D. Jadeja; Yehuda Shoenfeld; Mitesh Kumar Dwivedi

doi:10.1007/978-981-19-4800-8_3

COVID-19 and Autoimmunity

Prashant S. Giri, Shahnawaz D. Jadeja, Yehuda Shoenfeld, Mitesh Kumar Dwivedi^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19), caused by the continuously evolving novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a global health concern since the start of pandemic. Apart from other COVID-19 associated complications, emerging studies have suggested autoimmune manifestations following SARS-CoV-2. Additionally, autoantibodies have been detected in COVID-19 patients. COVID-19 can lead to autoimmune manifestations, through various mechanisms such as molecular mimicry, bystander activation, cytokine storm, generation of autoantibodies, and genetic susceptibility. Several autoimmune diseases like Guillain-Barre syndrome, immune thrombocytopenic purpura, autoimmune hemolytic anemia, autoimmune thyroid diseases, Kawasaki disease, and Alopecia areata have been linked with COVID-19. Additionally, autoimmune diseases have been linked with the increased risk of severe illness and mortality after SARS-CoV-2 infection. Therefore, understanding the pathophysiology of COVID-19 associated autoimmunity can aid in management and treatment of COVID-19.

Original language	English
Title of host publication	Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases
Subtitle of host publication	Volume II: Kidney, Central Nervous System, Eye, Blood, Blood Vessels and Bowel
Publisher	Springer Nature
Pages	57-84
Number of pages	28
Volume	2
ISBN (Electronic)	9789811948008
ISBN (Print)	9789811947995
DOIs	https://doi.org/10.1007/978-981-19-4800-8_3
State	Published - 1 Jan 2023
Externally published	Yes

Keywords

Autoimmune diseases
Autoimmunity
COVID-19
Coronavirus
SARS-CoV-2

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-981-19-4800-8_3

Cite this

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COVID-19 and Autoimmunity. / Giri, Prashant S.; Jadeja, Shahnawaz D.; Shoenfeld, Yehuda et al.
Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases: Volume II: Kidney, Central Nervous System, Eye, Blood, Blood Vessels and Bowel. Vol. 2 Springer Nature, 2023. p. 57-84.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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COVID-19 and Autoimmunity

Abstract

Keywords

UN SDGs

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