CO2 temperature controlled laser soldering of pig trachea incisions in vitro using flexible albumin bands

Dan Sharvit*, Tamar Vasilyev, Irena Vasserman, David Simhon, Naam Kariv, Ari DeRowe, Abraham Katzir

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations

Abstract

Resection of a segment of the trachea is a procedure applied for the removal of cervical tumors invading the trachea, or for the treatment of severe tracheal stenosis. The current method of anastomosis is based on multiple sutures. The main drawbacks of this method are: 1) A long procedure time, 2) An air leakage, and 3) An inflammatory response to the sutures. In this study we evaluated the feasibility and effectiveness of the use of temperature controlled CO2 laser soldering of incisions in pig tracheas in vitro. A transverse incision was made in a separated pig trachea. A flexible albumin band was prepared and was laser soldered with albumin solder to the outer surface of the trachea, covering the incision. The soldered trachea ends were sealed and the burst pressure was measured. In a series of in vitro experiments, the mean burst pressure was found to be 230 mm Hg. These preliminary results demonstrated that laser soldering using a flexible albumin band may be a useful method for sealing an incision in the trachea.

Original languageEnglish
Article number54
Pages (from-to)242-247
Number of pages6
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5686
DOIs
StatePublished - 2005
EventPhotonic Therapeutics and Diagnostics - San Jose, CA, United States
Duration: 22 Jan 200525 Jan 2005

Keywords

  • Anastomosis
  • Burst pressure
  • CO laser
  • Laser soldering
  • Pig
  • Solid albumin
  • Temperature control
  • Trachea

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