TY - JOUR
T1 - Corticosteroids in the Treatment of Optic Neuritis
AU - the Optic Neuritis Study Group
AU - Colucciello, Michael
AU - Brucker, Alexander J.
AU - Goyal, Anil
AU - Moskopp, Dag
AU - Achiron, Anat
AU - Djaldetti, Ruth
AU - Ziv, Ilan
AU - Beck, Roy W.
PY - 1992/7/23
Y1 - 1992/7/23
N2 - To the Editor:… A cause—effect relation between oral prednisone treatment of optic neuritis and the development of multiple sclerosis does not seem likely. Perhaps the higher incidence of recurrent optic neuritis in the prednisone group in the Optic Neuritis Treatment Trial (Feb. 27 issue)* represents a higher incidence of multiple sclerosis in this cohort. Should not this possibility be considered? Did the patients with multiple sclerosis in the study have a higher incidence of recurrent optic neuritis?.
AB - To the Editor:… A cause—effect relation between oral prednisone treatment of optic neuritis and the development of multiple sclerosis does not seem likely. Perhaps the higher incidence of recurrent optic neuritis in the prednisone group in the Optic Neuritis Treatment Trial (Feb. 27 issue)* represents a higher incidence of multiple sclerosis in this cohort. Should not this possibility be considered? Did the patients with multiple sclerosis in the study have a higher incidence of recurrent optic neuritis?.
UR - http://www.scopus.com/inward/record.url?scp=1642422806&partnerID=8YFLogxK
U2 - 10.1056/NEJM199207233270414
DO - 10.1056/NEJM199207233270414
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C2 - 1614478
AN - SCOPUS:1642422806
SN - 0028-4793
VL - 327
SP - 281
EP - 282
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 4
ER -