Corticosteroid induced remission of oesophageal involvement in mixed connective tissue disease

Amos Pines*, Ehud Goldhammer, Naomi Kaplinsky, Joseph Bregman, Otto Frankl

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Oesophageal involvement is known to be one of the most severe and resistant manifestations of connective tissue diseases, mainly progressive systemic sclerosis (PSS). A patient who had manifestations of systemic lupus erythematosus, PSS and polymyositis is described. Since some features of mixed connective tissue disease (MCTD) respond to corticosteroid treatment, fluocortolone was administered and both clinical and radiological remission of the oesophageal involvement were observed. At the same time, there was also a marked improvement of the cutaneous lesions. In view of the described observation, it seems advisable to try this treatment for oesophageal manifestations of MCTD.

Original languageEnglish
Pages (from-to)297-298
Number of pages2
JournalPostgraduate Medical Journal
Volume58
Issue number679
DOIs
StatePublished - 1982
Externally publishedYes

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