@article{cfbc360ad0524d329fe07bcfd6cddaf3,
title = "Correlates of vitamin D in psychotic disorders: A comprehensive systematic review",
abstract = "People with psychosis have high prevalence of low vitamin D levels but the correlates and relevance of this deficiency are unclear. A systematic search of major databases from inception to 03/2016 was undertaken investigating correlates of vitamin D in people with psychosis. Data was summarised with a best evidence synthesis. Across 23 included studies (n=1770 psychosis, n=8171 controls) a mean difference in vitamin D levels between both groups of −11.14 ng/ml±0.59 was found. 53 unique correlations between vitamin D and outcomes in people with psychosis were identified. The evidence base was broadly equivocal although season of blood sampling (67% of studies found a positive correlation with warmer seasons) and parathyroid hormone (100% of studies found a negative correlation) were associated with vitamin D levels. The most commonly non-correlated variables were: BMI (83% found no correlation), age (73%), gender (86%), smoking (100%), duration of illness (100%) and general assessment of functioning score (100%). In conclusion, whilst many unique correlates have been investigated, there is weak and inconclusive evidence regarding the consistency and meaning of the correlates of vitamin D levels in people with psychosis. Future longitudinal studies should consider the correlates of vitamin D in people with psychosis.",
keywords = "25-OHD, 25-hydroxyvitamin D, Hypovitaminosis D, Psychosis, Schizophrenia, Vitamin D",
author = "James Adamson and John Lally and Fiona Gaughran and Amir Krivoy and Lauren Allen and Brendon Stubbs",
note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ireland Ltd",
year = "2017",
month = mar,
day = "1",
doi = "10.1016/j.psychres.2016.12.052",
language = "אנגלית",
volume = "249",
pages = "78--85",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
}