Core/Shell Iron Oxide@Gold nanoparticles for dual-modal CT/MRI imaging

Oshra Betzer, Menachem Motiei, Tamar Dreifuss, Tamar Sadan, Noam Omer, Tamar Blumenfeld-Katzir, Zhuang Liu, Noam Ben-Eliezer, Rachela Popovtzer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations


Multimodal imaging, integrating different imaging modalities, is emerging as a promising strategy for improving both preclinical and clinical imaging. Computed tomography (CT) and magnetic resonance imaging (MRI) are among the widely clinically-used imaging techniques. These imaging modalities are used for disease diagnosis and screening, each providing different and complementary information about the patient and the disease state. Nanoparticles are considered promising contrast agents for in vivo imaging applications, providing improved imaging and targeting capabilities compared to the commonly used contrast compounds. In this project, we present the development of a novel hybrid nanostructure, comprising of iron oxide core and gold shell nanoparticle for dual model CT and MRI imaging. The hybrid structures presented herein have potential to serve as a unique platform for precision imaging.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII
EditorsDror Fixler, Ewa M. Goldys, Sebastian Wachsmann-Hogiu
ISBN (Electronic)9781510632714
StatePublished - 2020
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII 2020 - San Francisco, United States
Duration: 2 Feb 20203 Feb 2020

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII 2020
Country/TerritoryUnited States
CitySan Francisco


FundersFunder number
European Union Horizon 2020- research and innovation program
European Union Horizon 2020-research and innovation program761031
Ministry of Science Technology
Ministry of Science and Technology, Taiwan
Council for Higher Education


    • CT
    • Core-shell
    • Gold nanoparticles
    • Iron Oxide nanoparticles
    • MRI
    • Multimodal imaging


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