Cordocentesis in the evaluation of the growth-retarded fetus

The direct access to the fetal circulation provided by cordocentesis enables a better understanding of physiologic changes and more efficient diagnosis and treatment of many pathologic conditions. Because the procedure of direct fetal blood sampling is relatively safe, it has great potential in both antepartum surveillance and treatment of the severely growth-retarded fetus. Ultrasonography and Doppler instruments are the basis for urgently needed therapeutic trials which most probably will provide the obstetrician with new tools to treat the IUGR fetus early enough to prevent fetal compromise. Intrauterine infusion of nutrient supplements and methods to improve fetal acid-base balance may eventually be incorporated into the management protocols of the jeopardized growth-retarded fetus.