Coping with participant heterogeneity in dichotomous responses

Isaac Meilijson, Sara Meilijson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Participant heterogeneity induces spurious dependence that may obscure dependence patterns displayed by a covariance matrix. A parsimonious method is proposed for the reduction of this confounding effect. The method is applied to dichotomous behavioral response data of participants diagnosed with schizophrenia, as assessed by the Pragmatic Protocol (J. Speech Hear. Disord. 1987; 52:105-119).

Original languageEnglish
Pages (from-to)2042-2053
Number of pages12
JournalStatistics in Medicine
Issue number15
StatePublished - 10 Jul 2009


  • Covariance
  • Pragmatics of language
  • Schizophrenia
  • Severity


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