Convulsant benzodiazepine Ro 5-3663 has anxiolytic properties

J. Feldon, M. Myslobodsky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A hypothesis was tested that convulsant benzodiazepine would have a pronounced pro-anxiety action. Contrary to expectation, convulsant benzodiazepine with GABA antagonistic properties, Ro 5-3663, administered alone (1 mg/kg, IP) or together with chlordiazepoxide (5 mg/kg, IP) antagonized response suppression in the one-trial inhibitory learning task.

Original languageEnglish
Pages (from-to)689-691
Number of pages3
JournalPharmacology Biochemistry and Behavior
Issue number5
StatePublished - May 1982


  • Anxiety
  • Convulsant benzodiazepine
  • GABA


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